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*                        warfarinPK2_project.mlxtran                           *
*                        February 18, 2018 at 20:08:08                         *
*                        Monolix version : 5.0.0                               *
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POPULATION PARAMETERS ESTIMATION _______________________________________________

Fixed Effects ----------------------------     se_sa    rse(%)
ka_pop                         :       0.5                    
V_pop                          :      7.74     0.338      4.37
Cl_pop                         :     0.134   0.00689      5.12

Standard Deviation of the Random Effects -
omega_ka                       :      0.66     0.197      29.9
omega_V                        :     0.211    0.0333      15.8
omega_Cl                       :     0.274     0.039      14.3

Correlations -----------------------------
corr_V_Cl                      :     0.462     0.172      37.1

Error Model Parameters -------------------
a                              :     0.567    0.0987      17.4
b                              :      0.08    0.0181      22.6

Elapsed time (seconds) :     0.82
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CORRELATION MATRIX OF THE ESTIMATES ____________________________________________

Fisher by Stochastic Approximation ---------------------------------------------
Correlation Matrix :
    V_pop   1.00000
   Cl_pop   0.37201   1.00000
 omega_ka   0.01013   0.04215   1.00000
  omega_V   0.09301  -0.01555  -0.00646   1.00000
corr_V_Cl  -0.04939   0.02285   0.02423   0.18862   1.00000
 omega_Cl   0.01406   0.02496   0.01247   0.16546   0.18962   1.00000
        a  -0.05648   0.03069  -0.04141   0.00480   0.01248   0.00965   1.00000
        b   0.04652  -0.01623   0.04044  -0.04742   0.03076  -0.04545  -0.86008   1.00000
                               min       max   max/min
Eigen values           :      0.14       1.9        14

Elapsed time (seconds) :    0.17
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